Physical Examination 
• Enlarged lymph nodes in the neck, under the arms or in the groin.
• Swelling in the area of the tonsils, throat or upper airway.
• Fluid around the lungs (pleural effusion).
• Liver or spleen enlargement.
• Abdominal mass.
• Soft tissue swelling. 
• Tenderness when pressure is applied to areas of the skeleton.
• Neurologic findings such as numbness or muscle weakness.

Blood and Other Tests 
• Complete blood count may show circulating lymphoma cells or other blood abnormalities because of
  lymphoma in the bone marrow .
• Blood chemistries may be abnormal because of the tumor or because of the involvement of bone, lungs, the
  liver or the kidneys. 
• HIV test.